Serotonin in Brain Behavior: Drug-Induced Alterations Para-chlorophenylalanine Behavior: Neurochemically-induced Alterations Behavioral Assessment and Control Schedule-dependent Drug Effects Influence of Behavior on Transmitter
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Interaction of colchicine with nitric oxide in CA1 on the expression of drug seeking behavior induced by morphine
Introduction: According to previous studies, colchicine causes neuronal destruction and learning depression. In this project, effects of colchicine injection into the CA1 and interaction between colchicine and nitric oxide (NO) in this area on the expression of drug-seeking behavior were investigated. Methods: Wistar rats (250-300 g) were bilaterally cannulated at the CA1 area. Colchicine (2...
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Prenatal stress in rats results in structural, physiological and behavioral alterations that persist in adulthood. Serotonin (5-HT) is an important neurotransmitter known to be involved in these prenatal stress-induced behavioral alterations. The aim of the study was to investigate the effects of interrupted synthesis of 5-HT and immobilization stress during different gestational period on brai...
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STUDIES of drug-induced alterations in the total level of 5-hydroxytryptamine (5-HT) in whole brain or in specific brain regions have failed to show any trend consistent with simultaneous drug-induced behavioral changes. This has led us, along with other investigators in this field, to speculate that the size o,f the total cerebral store of a neurohumor may not be nearly as important a correlat...
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Introduction: Curcumin, a yellow-pigment, found in the popular Indian spice turmeric (Curcuma longa), poses pharmaceutical applications due to its anti-inflammatory, antioxidant, and chemoprotective properties. Excessive fluoride causes fluorosis leading to neurodegeneration and associated behavioral deficits, particularly in children. This study aimed at investigating the neuroprotective abili...
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Objective: This research revealed the biochemical outcomes of metabolic dysregulation in serum associated with physiological sickness behavior following lipopolysaccharide (LPS)-induced neuroinflammation in rats, and treatment with Clinacanthus nutans (CN). Verification of 1H NMR analysis of the CN aqueous extract proved the existence of bioactive phytochemical constituents’ in extract. Materia...
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